Partial Deletion of Tie2 Affects Microvascular Endothelial Responses to Critical Illness in A Vascular Bed and Organ-Specific Way

Tyrosine kinase receptor (Tie2) is mainly expressed by endothelial cells. In animal models mimicking critical illness, Tie2 levels in organs are temporarily reduced. Functional consequences of these reduced Tie2 levels on microvascular endothelial behavior are unknown. We investigated the effect of...

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Vydáno v:Shock
Hlavní autoři: Jongman, Rianne M., Zwiers, Peter J., van de Sluis, Bart, van der Laan, Marleen, Moser, Jill, Zijlstra, Jan G., Dekker, Daphne, Huijkman, Nicolette, Moorlag, Henk E., Popa, Eliane R., Molema, Grietje, van Meurs, Matijs
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2019
Témata:
Basic Science Aspects
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511431/
https://ncbi.nlm.nih.gov/pubmed/30520765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000001226
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