Low Serum Angiopoietin-1, High Serum Angiopoietin-2, and High Ang-2/Ang-1 Protein Ratio are Associated with Early Onset Sepsis in Surinamese Newborns

PURPOSE: Vascular inflammation and leakage in sepsis is mediated by Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) and their phosphorylation of the endothelial Tie-2 receptor. This study investigates levels of Ang-1 and Ang-2 in newborns to gain insight in the vascular pathophysiology of early on...

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Bibliographische Detailangaben
Veröffentlicht in:Shock
Hauptverfasser: Zonneveld, Rens, Jongman, Rianne, Juliana, Amadu, Zijlmans, Wilco, Plötz, Frans, Molema, Grietje, van Meurs, Matijs
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams & Wilkins 2017
Schlagworte:
Clinical Science Aspects
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647105/
https://ncbi.nlm.nih.gov/pubmed/28538018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000903
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