Angiopoietin/Tie2 Dysbalance Is Associated with Acute Kidney Injury after Cardiac Surgery Assisted by Cardiopulmonary Bypass

INTRODUCTION: The pathophysiology of acute kidney injury (AKI) after cardiac surgery is not completely understood. Recent evidence suggests a pivotal role for the endothelium in AKI. In experimental models of AKI, the endothelial specific receptor Tie2 with its ligands Angiopoietin (Ang) 1 and Ang2...

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Publicat a:PLoS One
Autors principals: Jongman, Rianne M., van Klarenbosch, Jan, Molema, Grietje, Zijlstra, Jan G., de Vries, Adrianus J., van Meurs, Matijs
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550386/
https://ncbi.nlm.nih.gov/pubmed/26309217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136205
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