Time course of angiopoietin-2 release during experimental human endotoxemia and sepsis

INTRODUCTION: Endothelial activation leading to vascular barrier breakdown denotes a devastating event in sepsis. Angiopoietin (Ang)-2, a circulating antagonistic ligand of the endothelial specific Tie2 receptor, is rapidly released from Weibel-Palade and has been identified as a non-redundant gatek...

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Main Authors: Kümpers, Philipp, van Meurs, Matijs, David, Sascha, Molema, Grietje, Bijzet, Johan, Lukasz, Alexander, Biertz, Frank, Haller, Hermann, Zijlstra, Jan G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717419/
https://ncbi.nlm.nih.gov/pubmed/19416526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc7866
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