The Proteogenomic Landscape of Curable Prostate Cancer

DNA sequencing has identified recurrent mutations that drive the aggressiveness of prostate cancers. Surprisingly, the influence of genomic, epigenomic and transcriptomic dysregulation on the tumor proteome remains poorly understood. We profiled the genomes, epigenomes, transcriptomes and proteomes...

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Détails bibliographiques
Publié dans:Cancer Cell
Auteurs principaux: Sinha, Ankit, Huang, Vincent, Livingstone, Julie, Wang, Jenny, Fox, Natalie S., Kurganovs, Natalie, Ignatchenko, Vladimir, Fritsch, Katharina, Donmez, Nilgun, Heisler, Lawrence E., Shiah, Yu-Jia, Yao, Cindy Q., Alfaro, Javier A., Volik, Stas, Lapuk, Anna, Fraser, Michael, Kron, Ken, Murison, Alex, Lupien, Mathieu, Sahinalp, Cenk, Collins, Colin C., Tetu, Bernard, Masoomian, Mehdi, Berman, David M., van der Kwast, Theodorus, Bristow, Robert G., Kislinger, Thomas, Boutros, Paul C.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511374/
https://ncbi.nlm.nih.gov/pubmed/30889379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2019.02.005
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