SETD3 is an Actin Histidine Methyltransferase that Prevents Primary Dystocia

For over fifty years, the methylation of mammalian actin at histidine 73 (actin-H73me) has been known to exist(1). Beyond mammals, we find that actin-H73me is conserved in several additional model animal and plant organisms. Despite the pervasiveness of H73me, its function is enigmatic, and the enzy...

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Publicat a:Nature
Autors principals: Wilkinson, Alex W., Diep, Jonathan, Dai, Shaobo, Liu, Shuo, Ooi, Yaw shin, Song, Dan, Li, Tie-Mei, Horton, John R., Zhang, Xing, Liu, Chao, Trivedi, Darshan V., Ruppel, Katherine M., Vilches-Moure, José G., Casey, Kerriann M., Mak, Justin, Cowan, Tina, Elias, Joshua E., Nagamine, Claude M., Spudich, James A., Cheng, Xiaodong, Carette, Jan E., Gozani, Or
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511263/
https://ncbi.nlm.nih.gov/pubmed/30626964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0821-8
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