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Accumulation of PNPLA3 on lipid droplets is the basis of associated hepatic steatosis
Fatty liver disease (FLD) is a disorder in which accumulation of triglycerides (TGs) in the liver can lead to inflammation, fibrosis, and cirrhosis. Previously, we identified a variant (I148M) in patatin-like phospholipase domain-containing protein 3 (PNPLA3) that is strongly associated with FLD, bu...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6511016/ https://ncbi.nlm.nih.gov/pubmed/31019090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901974116 |
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