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PNPLA3, CGI‐58, and Inhibition of Hepatic Triglyceride Hydrolysis in Mice

A variant (148M) in patatin‐like phospholipase domain‐containing protein 3 (PNPLA3) is a major risk factor for fatty liver disease. Despite its clinical importance, the pathogenic mechanism linking the variant to liver disease remains poorly defined. Previously, we showed that PNPLA3(148M) accumulat...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Wang, Yang, Kory, Nora, BasuRay, Soumik, Cohen, Jonathan C., Hobbs, Helen H.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563103/
https://ncbi.nlm.nih.gov/pubmed/30802989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30583
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