Impaired Renal Function May Not Negate the Efficacy of Tolvaptan in the Treatment of Cirrhotic Patients with Refractory Ascites

BACKGROUND AND OBJECTIVE: Tolvaptan, an oral vasopressin V2 receptor antagonist, has been widely used for the treatment of patients with cirrhosis and ascites. However, its efficacy in patients with renal dysfunction remains unknown. The objective of this study was to investigate the efficacy and sa...

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Veröffentlicht in:Clin Drug Investig
Hauptverfasser: Arase, Yoshitaka, Kagawa, Tatehiro, Tsuruya, Kota, Sato, Hirohiko, Teramura, Erika, Anzai, Kazuya, Hirose, Shunji, Deguchi, Ryuzo, Shiraishi, Koichi, Mine, Tetsuya
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2018
Schlagworte:
Original Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510826/
https://ncbi.nlm.nih.gov/pubmed/30284699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40261-018-0714-5
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