Impaired Renal Function May Not Negate the Efficacy of Tolvaptan in the Treatment of Cirrhotic Patients with Refractory Ascites

BACKGROUND AND OBJECTIVE: Tolvaptan, an oral vasopressin V2 receptor antagonist, has been widely used for the treatment of patients with cirrhosis and ascites. However, its efficacy in patients with renal dysfunction remains unknown. The objective of this study was to investigate the efficacy and sa...

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Dettagli Bibliografici
Pubblicato in:Clin Drug Investig
Autori principali: Arase, Yoshitaka, Kagawa, Tatehiro, Tsuruya, Kota, Sato, Hirohiko, Teramura, Erika, Anzai, Kazuya, Hirose, Shunji, Deguchi, Ryuzo, Shiraishi, Koichi, Mine, Tetsuya
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2018
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Original Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510826/
https://ncbi.nlm.nih.gov/pubmed/30284699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40261-018-0714-5
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