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Impaired Renal Function May Not Negate the Efficacy of Tolvaptan in the Treatment of Cirrhotic Patients with Refractory Ascites

BACKGROUND AND OBJECTIVE: Tolvaptan, an oral vasopressin V2 receptor antagonist, has been widely used for the treatment of patients with cirrhosis and ascites. However, its efficacy in patients with renal dysfunction remains unknown. The objective of this study was to investigate the efficacy and sa...

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Publicado en:Clin Drug Investig
Main Authors: Arase, Yoshitaka, Kagawa, Tatehiro, Tsuruya, Kota, Sato, Hirohiko, Teramura, Erika, Anzai, Kazuya, Hirose, Shunji, Deguchi, Ryuzo, Shiraishi, Koichi, Mine, Tetsuya
Formato: Artigo
Idioma:Inglês
Publicado: Springer International Publishing 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510826/
https://ncbi.nlm.nih.gov/pubmed/30284699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40261-018-0714-5
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