Trabectedin and RAdiotherapy in Soft Tissue Sarcoma (TRASTS): Results of a Phase I Study in Myxoid Liposarcoma from Spanish (GEIS), Italian (ISG), French (FSG) Sarcoma Groups

BACKGROUND: Myxoid liposarcoma (ML) exhibits a special sensitivity to trabectedin (T) and radiation therapy (RT). Preclinical data suggest a synergistic effect. We aimed to study safety, feasibility and activity of the administration of pre-operative concurrent T and RT in patients affected by local...

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Detalles Bibliográficos
Publicado en:EClinicalMedicine
Main Authors: Gronchi, Alessandro, Hindi, Nadia, Cruz, Josefina, Blay, Jean-Yves, Lopez-Pousa, Antonio, Italiano, Antoine, Alvarez, Rosa, Gutierrez, Antonio, Rincón, Inmaculada, Sangalli, Claudia, Pérez Aguiar, Jose Luis, Romero, Jesús, Morosi, Carlo, Sunyach, Marie Pierre, Sanfilippo, Roberta, Romagosa, Cleofe, Ranchere-Vince, Dominique, Dei Tos, Angelo P., Casali, Paolo G., Martin-Broto, Javier
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2019
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510725/
https://ncbi.nlm.nih.gov/pubmed/31143880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eclinm.2019.03.007
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