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A multiscale model of epigenetic heterogeneity-driven cell fate decision-making

The inherent capacity of somatic cells to switch their phenotypic status in response to damage stimuli in vivo might have a pivotal role in ageing and cancer. However, how the entry-exit mechanisms of phenotype reprogramming are established remains poorly understood. In an attempt to elucidate such...

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Xehetasun bibliografikoak
Argitaratua izan da:PLoS Comput Biol
Egile Nagusiak: Folguera-Blasco, Núria, Pérez-Carrasco, Rubén, Cuyàs, Elisabet, Menendez, Javier A., Alarcón, Tomás
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510448/
https://ncbi.nlm.nih.gov/pubmed/31039148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006592
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