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A multiscale model of epigenetic heterogeneity-driven cell fate decision-making
The inherent capacity of somatic cells to switch their phenotypic status in response to damage stimuli in vivo might have a pivotal role in ageing and cancer. However, how the entry-exit mechanisms of phenotype reprogramming are established remains poorly understood. In an attempt to elucidate such...
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| Publicado no: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6510448/ https://ncbi.nlm.nih.gov/pubmed/31039148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006592 |
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