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Human Pentraxins Bind to Misfolded Proteins and Inhibit Production of Type I Interferon Induced by Nucleic Acid-Containing Amyloid

OBJECTIVE: Amyloid deposition is linked to multiple human ailments, including neurodegenerative diseases, type 2 diabetes, and systemic amyloidosis. The assembly of misfolded proteins into amyloid fibrils involves an intermediate form, i.e., soluble amyloid precursor (AP), which exerts cytotoxic fun...

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Bibliographic Details
Published in:J Clin Cell Immunol
Main Authors: Dorta-Estremera, Stephanie M, Cao, Wei
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510259/
https://ncbi.nlm.nih.gov/pubmed/31080694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-9899.1000332
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