WIP1 Contributes to the Adaptation of Fanconi Anemia Cells to DNA Damage as Determined by the Regulatory Network of the Fanconi Anemia and Checkpoint Recovery Pathways

DNA damage adaptation (DDA) allows the division of cells with unrepaired DNA damage. DNA repair deficient cells might take advantage of DDA to survive. The Fanconi anemia (FA) pathway repairs DNA interstrand crosslinks (ICLs), and deficiencies in this pathway cause a fraction of breast and ovarian c...

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Udgivet i:Front Genet
Main Authors: Rodríguez, Alfredo, Naveja, J. Jesús, Torres, Leda, García de Teresa, Benilde, Juárez-Figueroa, Ulises, Ayala-Zambrano, Cecilia, Azpeitia, Eugenio, Mendoza, Luis, Frías, Sara
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Genetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509935/
https://ncbi.nlm.nih.gov/pubmed/31130988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00411
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