WIP1 Contributes to the Adaptation of Fanconi Anemia Cells to DNA Damage as Determined by the Regulatory Network of the Fanconi Anemia and Checkpoint Recovery Pathways

DNA damage adaptation (DDA) allows the division of cells with unrepaired DNA damage. DNA repair deficient cells might take advantage of DDA to survive. The Fanconi anemia (FA) pathway repairs DNA interstrand crosslinks (ICLs), and deficiencies in this pathway cause a fraction of breast and ovarian c...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Rodríguez, Alfredo, Naveja, J. Jesús, Torres, Leda, García de Teresa, Benilde, Juárez-Figueroa, Ulises, Ayala-Zambrano, Cecilia, Azpeitia, Eugenio, Mendoza, Luis, Frías, Sara
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509935/
https://ncbi.nlm.nih.gov/pubmed/31130988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00411
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