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A Cautionary Note on the Effects of Population Stratification Under an Extreme Phenotype Sampling Design

Extreme phenotype sampling (EPS) is a popular study design used to reduce genotyping or sequencing costs. Assuming continuous phenotype data are available on a large cohort, EPS involves genotyping or sequencing only those individuals with extreme phenotypic values. Although this design has been sho...

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Bibliografische gegevens
Gepubliceerd in:Front Genet
Hoofdauteurs: Panarella, Michela, Burkett, Kelly M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509877/
https://ncbi.nlm.nih.gov/pubmed/31130982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00398
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