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A Cautionary Note on Using Secondary Phenotypes in Neuroimaging Genetic Studies

Almost all genome-wide association studies (GWASs), including Alzheimer’s Disease Neuroimaging Initiative (ADNI), are based on the case-control study design, implying that the resulting case-control data are likely a biased, not random, sample of the target population. Although association analysis...

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Detalhes bibliográficos
Publicado no:Neuroimage
Main Authors: Kim, Junghi, Pan, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604049/
https://ncbi.nlm.nih.gov/pubmed/26220747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2015.07.058
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