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A Cautionary Note on the Effects of Population Stratification Under an Extreme Phenotype Sampling Design

Extreme phenotype sampling (EPS) is a popular study design used to reduce genotyping or sequencing costs. Assuming continuous phenotype data are available on a large cohort, EPS involves genotyping or sequencing only those individuals with extreme phenotypic values. Although this design has been sho...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Panarella, Michela, Burkett, Kelly M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509877/
https://ncbi.nlm.nih.gov/pubmed/31130982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00398
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