Absence of BBSome function leads to astrocyte reactivity in the brain

In humans, dysfunctional primary cilia result in Bardet-Biedl syndrome (BBS), which presents with clinical features including intellectual disabilities, obesity, and retinal degeneration, and, in mouse models, the added feature of hydrocephalus. We observed increased Glial Fibrillary Acidic Protein...

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Bibliografiske detaljer
Udgivet i:Mol Brain
Main Authors: Singh, Minati, Garrison, Janelle E., Wang, Kai, Sheffield, Val C.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509862/
https://ncbi.nlm.nih.gov/pubmed/31072410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-019-0466-z
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