Absence of BBSome function leads to astrocyte reactivity in the brain

In humans, dysfunctional primary cilia result in Bardet-Biedl syndrome (BBS), which presents with clinical features including intellectual disabilities, obesity, and retinal degeneration, and, in mouse models, the added feature of hydrocephalus. We observed increased Glial Fibrillary Acidic Protein...

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Bibliographic Details
Published in:Mol Brain
Main Authors: Singh, Minati, Garrison, Janelle E., Wang, Kai, Sheffield, Val C.
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509862/
https://ncbi.nlm.nih.gov/pubmed/31072410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-019-0466-z
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