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Absence of BBSome function leads to astrocyte reactivity in the brain

In humans, dysfunctional primary cilia result in Bardet-Biedl syndrome (BBS), which presents with clinical features including intellectual disabilities, obesity, and retinal degeneration, and, in mouse models, the added feature of hydrocephalus. We observed increased Glial Fibrillary Acidic Protein...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Singh, Minati, Garrison, Janelle E., Wang, Kai, Sheffield, Val C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509862/
https://ncbi.nlm.nih.gov/pubmed/31072410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-019-0466-z
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