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Efficient reduction of synthetic mRNA induced immune activation by simultaneous delivery of B18R encoding mRNA
The application of synthetic modified messenger RNA (mRNA) is a promising approach for the treatment of a variety of diseases and vaccination. In the past few years, different modifications of synthetic mRNA were applied to render the mRNA more stable and less immunogenic. However, the repeated appl...
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| Publicado no: | J Biol Eng |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6509845/ https://ncbi.nlm.nih.gov/pubmed/31168319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-019-0172-5 |
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