Toll‐Like Receptor 9 Plays a Pivotal Role in Angiotensin II–Induced Atherosclerosis

BACKGROUND: Toll‐like receptor (TLR) 9 recognizes bacterial DNA, activating innate immunity, whereas it also provokes inflammation in response to fragmented DNA released from mammalian cells. We investigated whether TLR9 contributes to the development of vascular inflammation and atherogenesis using...

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Publicado en:J Am Heart Assoc
Autores principales: Fukuda, Daiju, Nishimoto, Sachiko, Aini, Kunduziayi, Tanaka, Atsushi, Nishiguchi, Tsuyoshi, Kim‐Kaneyama, Joo‐ri, Lei, Xiao‐Feng, Masuda, Kiyoshi, Naruto, Takuya, Tanaka, Kimie, Higashikuni, Yasutomi, Hirata, Yoichiro, Yagi, Shusuke, Kusunose, Kenya, Yamada, Hirotsugu, Soeki, Takeshi, Imoto, Issei, Akasaka, Takashi, Shimabukuro, Michio, Sata, Masataka
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509720/
https://ncbi.nlm.nih.gov/pubmed/30905257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.010860
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