Canagliflozin Prevents Diabetes-Induced Vascular Dysfunction in ApoE-Deficient Mice

Aim: Recent studies have demonstrated that selective sodium–glucose cotransporter 2 inhibitors (SGLT2is) reduce cardiovascular events, although their mechanism remains obscure. We examined the effect of canagliflozin, an SGLT2i, on atherogenesis and investigated its underlying mechanism. Method: Can...

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Vydáno v:J Atheroscler Thromb
Hlavní autoři: Rahadian, Arief, Fukuda, Daiju, Salim, Hotimah Masdan, Yagi, Shusuke, Kusunose, Kenya, Yamada, Hirotsugu, Soeki, Takeshi, Sata, Masataka
Médium: Artigo
Jazyk:Inglês
Vydáno: Japan Atherosclerosis Society 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803832/
https://ncbi.nlm.nih.gov/pubmed/32101837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5551/jat.52100
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