Glycemic Control with Ipragliflozin, a Novel Selective SGLT2 Inhibitor, Ameliorated Endothelial Dysfunction in Streptozotocin-Induced Diabetic Mouse

BACKGROUND: Endothelial dysfunction caused by increased oxidative stress is a critical initiator of macro- and micro-vascular disease development in diabetic patients. Ipragliflozin, a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor, offers a novel approach for the treatment of diabetes b...

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Bibliografische gegevens
Gepubliceerd in:Front Cardiovasc Med
Hoofdauteurs: Salim, Hotimah Masdan, Fukuda, Daiju, Yagi, Shusuke, Soeki, Takeshi, Shimabukuro, Michio, Sata, Masataka
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2016
Onderwerpen:
Cardiovascular Medicine
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080286/
https://ncbi.nlm.nih.gov/pubmed/27833913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2016.00043
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