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Ablation of elongation factor 2 kinase enhances heat-shock protein 90 chaperone expression and protects cells under proteotoxic stress

Eukaryotic elongation factor 2 kinase (eEF2K) negatively regulates the elongation stage of mRNA translation and is activated under different stress conditions to slow down protein synthesis. One effect of eEF2K is to alter the repertoire of expressed proteins, perhaps to aid survival of stressed cel...

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Foilsithe in:J Biol Chem
Main Authors: Van Damme, Petra, Proud, Christopher G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509509/
https://ncbi.nlm.nih.gov/pubmed/30890561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC119.008036
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