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Identification of mammalian glycoproteins with type-I LacdiNAc structures synthesized by the glycosyltransferase B3GALNT2

The type-I LacdiNAc (LDN; GalNAcβ1–3GlcNAc) has rarely been observed in mammalian cells except in the O-glycan of α-dystroglycan, in contrast to type-II LDN structures (GalNAcβ1–4GlcNAc) in N- and O-glycans that are present in many mammalian glycoproteins, such as pituitary and hypothalamic hormones...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Nakane, Takahiro, Angata, Kiyohiko, Sato, Takashi, Kaji, Hiroyuki, Narimatsu, Hisashi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509504/
https://ncbi.nlm.nih.gov/pubmed/30898876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006892
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