Molecular Basis for Recognition of the Cancer Glycobiomarker, LacdiNAc (GalNAc[β1→4]GlcNAc), by Wisteria floribunda Agglutinin

Aberrant glycosylation and the overexpression of specific carbohydrate epitopes is a hallmark of many cancers, and tumor-associated oligosaccharides are actively investigated as targets for immunotherapy and diagnostics. Wisteria floribunda agglutinin (WFA) is a legume lectin that recognizes termina...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Haji-Ghassemi, Omid, Gilbert, Michel, Spence, Jenifer, Schur, Melissa J., Parker, Matthew J., Jenkins, Meredith L., Burke, John E., van Faassen, Henk, Young, N. Martin, Evans, Stephen V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5104934/
https://ncbi.nlm.nih.gov/pubmed/27601469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.750463
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