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The host cell ubiquitin ligase protein CHIP is a potent suppressor of HIV-1 replication
Human immunodeficiency virus-1 (HIV-1) Tat is degraded in the host cell both by proteasomal and lysosomal pathways, but the specific molecules that engage with Tat from these pathways are not known. Because E3 ubiquitin ligases are the primary determinants of substrate specificity within the ubiquit...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6509501/ https://ncbi.nlm.nih.gov/pubmed/30885946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007257 |
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