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The host cell ubiquitin ligase protein CHIP is a potent suppressor of HIV-1 replication
Human immunodeficiency virus-1 (HIV-1) Tat is degraded in the host cell both by proteasomal and lysosomal pathways, but the specific molecules that engage with Tat from these pathways are not known. Because E3 ubiquitin ligases are the primary determinants of substrate specificity within the ubiquit...
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| 出版年: | J Biol Chem |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2019
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6509501/ https://ncbi.nlm.nih.gov/pubmed/30885946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007257 |
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