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Prion-like low-complexity sequences: Key regulators of protein solubility and phase behavior
Many proteins, such as RNA-binding proteins, have complex folding landscapes. How cells maintain the solubility and folding state of such proteins, particularly under stress conditions, is largely unknown. Here, we argue that prion-like low-complexity regions (LCRs) are key regulators of protein sol...
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| Udgivet i: | J Biol Chem |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6509491/ https://ncbi.nlm.nih.gov/pubmed/29921587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.TM118.001190 |
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