In silico Identification and Mechanism Exploration of Hepatotoxic Ingredients in Traditional Chinese Medicine

BACKGROUNDS AND AIMS: Recently, a growing number of hepatotoxicity cases aroused by Traditional Chinese Medicine (TCM) have been reported, causing increasing concern. To date, the reported predictive models for drug induced liver injury show low prediction accuracy and there are still no related rep...

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Vydáno v:Front Pharmacol
Hlavní autoři: Wu, Qihui, Cai, Chuipu, Guo, Pengfei, Chen, Meiling, Wu, Xiaoqin, Zhou, Jingwei, Luo, Yunxia, Zou, Yidan, Liu, Ai-lin, Wang, Qi, Kuang, Zaoyuan, Fang, Jiansong
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509242/
https://ncbi.nlm.nih.gov/pubmed/31130860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00458
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