In silico Identification and Mechanism Exploration of Hepatotoxic Ingredients in Traditional Chinese Medicine

BACKGROUNDS AND AIMS: Recently, a growing number of hepatotoxicity cases aroused by Traditional Chinese Medicine (TCM) have been reported, causing increasing concern. To date, the reported predictive models for drug induced liver injury show low prediction accuracy and there are still no related rep...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Wu, Qihui, Cai, Chuipu, Guo, Pengfei, Chen, Meiling, Wu, Xiaoqin, Zhou, Jingwei, Luo, Yunxia, Zou, Yidan, Liu, Ai-lin, Wang, Qi, Kuang, Zaoyuan, Fang, Jiansong
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Pharmacology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509242/
https://ncbi.nlm.nih.gov/pubmed/31130860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00458
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