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Mutant huntingtin disturbs circadian clock gene expression and sleep patterns in Drosophila

Deficiency of the sleep-wake cycle can accelerate the progression of Huntington’s disease (HD) and exacerbate symptoms making it a target of investigation to better understand the molecular pathology of the disorder. In this study we analyzed sleep defects in a Drosophila model of HD and investigate...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Faragó, Anikó, Zsindely, Nóra, Bodai, László
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509128/
https://ncbi.nlm.nih.gov/pubmed/31073199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43612-w
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