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Therapeutic Targeting of Endosomal G-Protein-Coupled Receptors
G-protein-coupled receptors (GPCRs) are conventionally considered to function at the plasma membrane, where they detect extracellular ligands and activate heterotrimeric G proteins that transmit intracellular signals. Consequently, drug discovery efforts have focused on identification of agonists an...
שמור ב:
| הוצא לאור ב: | Trends Pharmacol Sci |
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| Main Authors: | , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6508874/ https://ncbi.nlm.nih.gov/pubmed/30180973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2018.08.003 |
| תגים: |
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