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Engineering therapeutic antibodies targeting G-protein–coupled receptors
G-protein–coupled receptors (GPCRs) are one of the most attractive therapeutic target classes because of their critical roles in intracellular signaling and their clinical relevance to a variety of diseases, including cancer, infection and inflammation. However, high conformational variability, the...
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| 出版年: | Exp Mol Med |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4892866/ https://ncbi.nlm.nih.gov/pubmed/26846450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2015.105 |
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