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Finding driver mutations in cancer: Elucidating the role of background mutational processes

Identifying driver mutations in cancer is notoriously difficult. To date, recurrence of a mutation in patients remains one of the most reliable markers of mutation driver status. However, some mutations are more likely to occur than others due to differences in background mutation rates arising from...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Brown, Anna-Leigh, Li, Minghui, Goncearenco, Alexander, Panchenko, Anna R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508748/
https://ncbi.nlm.nih.gov/pubmed/31034466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006981
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