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Annotating mutational effects on proteins and protein interactions: designing novel and revisiting existing protocols

In this review we describe a protocol to annotate the effects of missense mutations on proteins, their functions, stability, and binding. For this purpose we present a collection of the most comprehensive databases which store different types of sequencing data on missense mutations, we discuss thei...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Li, Minghui, Goncearenco, Alexander, Panchenko, Anna R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388446/
https://ncbi.nlm.nih.gov/pubmed/28188534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-6747-6_17
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