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MutaBind estimates and interprets the effects of sequence variants on protein–protein interactions

Proteins engage in highly selective interactions with their macromolecular partners. Sequence variants that alter protein binding affinity may cause significant perturbations or complete abolishment of function, potentially leading to diseases. There exists a persistent need to develop a mechanistic...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Li, Minghui, Simonetti, Franco L., Goncearenco, Alexander, Panchenko, Anna R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987923/
https://ncbi.nlm.nih.gov/pubmed/27150810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw374
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