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MutaBind estimates and interprets the effects of sequence variants on protein–protein interactions

Proteins engage in highly selective interactions with their macromolecular partners. Sequence variants that alter protein binding affinity may cause significant perturbations or complete abolishment of function, potentially leading to diseases. There exists a persistent need to develop a mechanistic...

詳細記述

保存先:
書誌詳細
出版年:Nucleic Acids Res
主要な著者: Li, Minghui, Simonetti, Franco L., Goncearenco, Alexander, Panchenko, Anna R.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987923/
https://ncbi.nlm.nih.gov/pubmed/27150810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw374
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