Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer’s disease mouse models

Cerebral blood flow (CBF) reductions in Alzheimer’s disease (AD) patients and related mouse models have been recognized for decades, but the underlying mechanisms and resulting consequences on AD pathogenesis remain poorly understood. In APP/PS1 and 5xFAD mice we found that an increased number of co...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Nat Neurosci
Glavni autori: Cruz Hernández, Jean C., Bracko, Oliver, Kersbergen, Calvin J., Muse, Victorine, Haft-Javaherian, Mohammad, Berg, Maxime, Park, Laibaik, Vinarcsik, Lindsay K., Ivasyk, Iryna, Rivera, Daniel A., Kang, Yiming, Cortes-Canteli, Marta, Peyrounette, Myriam, Doyeux, Vincent, Smith, Amy, Zhou, Joan, Otte, Gabriel, Beverly, Jeffrey D., Davenport, Elizabeth, Davit, Yohan, Lin, Charles P., Strickland, Sidney, Iadecola, Costantino, Lorthois, Sylvie, Nishimura, Nozomi, Schaffer, Chris B.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508667/
https://ncbi.nlm.nih.gov/pubmed/30742116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0329-4
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items