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A100 PANCREASTATIN WORSENS INTESTINAL INFLAMMATION BY INDUCING CLASSICALLY ACTIVATED MACROPHAGES (M1) THROUGH SUPPRESSION OF STAT3
BACKGROUND: Chromogranin-A (CHGA) levels are increased in inflammatory bowel disease (IBD) and murine models of colitis. CHGA is cleaved in several peptides including the immunoregulatory pancreastatin (PST: CHGA(273-301)), which encodes by CHGA exon-VII. Classically activated macrophages (M1) and s...
Tallennettuna:
| Julkaisussa: | J Can Assoc Gastroenterol |
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| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6508373/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy009.100 |
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