A85 SEMAPHORIN-3E AMELIORATES INTESTINAL INFLAMMATION BY REGULATING EXPRESSION OF TIGHT JUNCTION PROTEIN AND PROINFLAMMATORY MEDIATORS

BACKGROUND: Ulcerative colitis (UC) is characterized by an alterations of tight junction (TJ) barrier and immune responses that result in abnormal passages of exogenous antigens such as gut-derived bacterial lipopolysaccharides (LPS). Semaphorin-3E (Sema3E) and its receptor plexin D1 (PLXD1R) are ke...

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Publicado en:J Can Assoc Gastroenterol
Main Authors: Kermarrec, L, Eissa, N, Soussi Gounni, A, Bernstein, C N, Ghia, J
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508391/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy009.085
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