A289 DELTA OPIOID RECEPTOR ACTIVATION TRIGGERS BOTH ANTINOCICEPTIVE AND PRONOCICEPTIVE SIGNALING

BACKGROUND: Opioid drugs are efficacious in the treatment of abdominal pain but increasing doses can activate pronociceptive signaling and paradoxically worsen pain. Although the mu opioid receptor (MOR) has been the classic analgesic target implicated in this signaling, there is growing evidence th...

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Detalhes bibliográficos
Publicado no:J Can Assoc Gastroenterol
Main Authors: Jaramillo Polanco, J O, Lopez Lopez, C D, Reed, D E, Lomax, A E, Vanner, S
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Paper Sessions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508328/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy009.289
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