A289 DELTA OPIOID RECEPTOR ACTIVATION TRIGGERS BOTH ANTINOCICEPTIVE AND PRONOCICEPTIVE SIGNALING

BACKGROUND: Opioid drugs are efficacious in the treatment of abdominal pain but increasing doses can activate pronociceptive signaling and paradoxically worsen pain. Although the mu opioid receptor (MOR) has been the classic analgesic target implicated in this signaling, there is growing evidence th...

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Bibliografski detalji
Izdano u:J Can Assoc Gastroenterol
Glavni autori: Jaramillo Polanco, J O, Lopez Lopez, C D, Reed, D E, Lomax, A E, Vanner, S
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Paper Sessions
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508328/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy009.289
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