A119 THE MICROBIAL METABOLITE SENSOR PREGNANE X RECEPTOR (PXR) RESTRAINS FIBROBLASTS FROM PROMOTING INTESTINAL INFLAMMATION AND FIBROSIS IN MICE

BACKGROUND: Fibrosis contributes to intestinal stricture and obstruction in 30–50% of Crohn’s disease patients. The pathogenesis of fibrosis is incompletely understood and has virtually no effective treatments. The pregnane X receptor (PXR), a xenobiotic receptor involved in detoxification responses...

全面介紹

Na minha lista:
書目詳細資料
發表在:J Can Assoc Gastroenterol
Main Authors: Flannigan, K L, Alston, L, Mani, S, Hirota, S A
格式: Artigo
語言:Inglês
出版: Oxford University Press 2018
主題:
Poster Presentations
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6507898/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy008.120
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍