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A137 PANCREASTATIN (PTS) EXACERBATES COLONIC INFLAMMATION

BACKGROUND: Chromogranin-A (CgA) is elevated in inflammatory bowel disease (IBD) and in murine models of colitis. CgA produced by enteroendocrine cells can be cleaved in several peptides including the immunoregulatory pancreastatin (PTS: CgA(273-301)). Macrophages (Mo) play a major role in IBD throu...

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發表在:J Can Assoc Gastroenterol
Main Authors: Eissa, N, Kermarrec, L, Bernstein, C N, Ghia, J
格式: Artigo
語言:Inglês
出版: Oxford University Press 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6507797/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy008.138
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