A31 REPROGRAMMING OF EXHAUSTED T CELLS FOLLOWING CURE OF CHRONIC VIRAL INFECTION

BACKGROUND: T-cell exhaustion is a hallmark of immunological failure to control chronic viral infection and cancer. Blocking inhibitory receptors such as programmed death-1 (PD-1) can re-invigorate exhausted T cells (T(EX)) in animal models of chronic viral infection and in cancer patients. However,...

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Dettagli Bibliografici
Pubblicato in:J Can Assoc Gastroenterol
Autori principali: Abdel-Hakeem, M S, Tonnerre, P, Khan, O, Stelekati, E, Ali, M, Lauer, G M, Wherry, E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
Soggetti:
Oral Presentations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6507592/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy008.032
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