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A211 PROTEOLYTIC CLEAVAGE OF E-CADHERIN BY INFLAMMATORY PROTEASES PRODUCES BIOACTIVE PEPTIDES THAT MODIFY EPITHELIAL FUNCTION

BACKGROUND: The inflammatory microenvironment in the gut contains a variety of proteases from numerous sources including inflammatory cells. We have been studying the ability of proteases to induce a switch in the colonic epithelium from a barrier to a repair phenotype (epithelial to mesenchymal tra...

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Foilsithe in:J Can Assoc Gastroenterol
Main Authors: Gordon, M, MacNaughton, W
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6507568/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy008.212
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