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Proteolytic activation of a bioactive cardiac peptide by in vitro trypsin cleavage.

Mammalian cardiac atria possess several unidentified biologically active peptides. Fractionation of rat atrial extracts by gel filtration chromatography revealed two major fractions [apparent molecular weights of 20,000-30,000 (peak I) and less than 10,000 (peak II)], both of which were potent natri...

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Autors principals: Currie, M G, Geller, D M, Cole, B R, Needleman, P
Format: Artigo
Idioma:Inglês
Publicat: 1984
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC344800/
https://ncbi.nlm.nih.gov/pubmed/6230673
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